In the First World War, iodine was found by Alexander Fleming to reduce the incidence of gas gangrene in the wounds of soldiers when compared to carbolic acid.
Povidone-iodine was first released and quickly became the universally preferred iodine disinfectant.
Povidone-iodine preparations were introduced as an iodophor and its slow release of iodine within the formula was found to reduce the sting and irritation of traditional iodine treatments.
BETADINE® is registered as a trademark and launched in several international markets.
BETADINE® antiseptic was chosen by NASA to wipe down Apollo 11 when it landed to sterilise the spacecraft against any space bacteria that might have hitched a ride.